KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
20.91
Human Site:
S1058
Identified Species:
38.33
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
S1058
Q
H
L
H
E
V
L
S
R
A
D
P
K
K
A
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
S1058
Q
H
L
H
E
V
L
S
R
A
D
P
K
K
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
S1040
K
Y
L
H
E
V
L
S
R
A
D
P
Q
K
A
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
S1065
K
H
L
H
E
V
L
S
R
A
D
P
Q
K
V
Rat
Rattus norvegicus
O54889
1716
194174
S1065
K
H
L
H
E
V
L
S
R
A
D
P
Q
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
A781
S
N
S
P
L
I
M
A
L
C
G
S
K
G
S
Frog
Xenopus laevis
NP_001082182
1730
195193
S1063
K
R
L
D
E
V
L
S
R
V
N
T
E
Q
A
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
A1051
K
C
L
D
E
V
L
A
K
M
D
P
V
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
P1029
N
A
T
A
I
L
R
P
A
Q
L
Q
L
M
K
Honey Bee
Apis mellifera
XP_001121092
1665
190473
K1012
E
E
M
I
K
K
L
K
E
D
S
D
T
D
K
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
D1094
S
K
P
E
G
V
T
D
A
D
F
G
I
K
E
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
V1057
Q
S
K
Y
R
G
P
V
N
D
P
S
Q
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
F1048
A
D
G
T
L
V
Q
F
M
Y
G
G
D
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
80
N.A.
80
80
N.A.
N.A.
6.6
46.6
46.6
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
40
73.3
66.6
N.A.
6.6
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
0
16
16
39
0
0
0
24
39
% A
% Cys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
16
0
0
0
8
0
24
47
8
8
8
0
% D
% Glu:
8
8
0
8
54
0
0
0
8
0
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
0
0
0
16
16
0
8
0
% G
% His:
0
31
0
39
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
8
0
0
0
0
0
0
8
0
8
% I
% Lys:
39
8
8
0
8
8
0
8
8
0
0
0
24
47
16
% K
% Leu:
0
0
54
0
16
8
62
0
8
0
8
0
8
0
0
% L
% Met:
0
0
8
0
0
0
8
0
8
8
0
0
0
8
0
% M
% Asn:
8
8
0
0
0
0
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
8
8
0
0
8
47
0
0
0
% P
% Gln:
24
0
0
0
0
0
8
0
0
8
0
8
31
8
0
% Q
% Arg:
0
8
0
0
8
0
8
0
47
0
0
0
0
0
0
% R
% Ser:
16
8
8
0
0
0
0
47
0
0
8
16
0
0
8
% S
% Thr:
0
0
8
8
0
0
8
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
70
0
8
0
8
0
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _